Sterilization of chitosan membranes for use as biomaterial

ARTIGO - 03/10/2014 - 11:01

Fook, Marcus Vinícius Lia; MEIRA, R. C. ; NASCIMENTO, I. V. S. R. ; LEAL, R. C. A. . STERILIZATION OF CHITOSAN MEMBRANES FOR USE AS BIOMATERIAL. Materials Science Forum (Online) , v. 805, p. 35, 2015.

Sterilization is a procedure which promotes complete destruction or elimination of all forms of microorganisms. It is a fundamental stage in the processing of biomaterials, and functionality of any sterilization system must be determined by its effectiveness in exterminating microorganisms without harming or adversely affect the properties of medical devices. Some sterilization techniques can react with functional groups of the polymer leading to changes in the properties, affecting the biomaterial. This study aimed to develop chitosan membranes sterilize them by following methods: an autoclave, ethylene oxide, glutaraldehyde and ultraviolet radiation and characterized by FTIR, XRD and SEM. Based on the results of this study it can be concluded that the method of sterilization indicated for the membranes of chitosan is ethylene oxide because the other altered physicochemical properties thereof.

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